Sustained-release formulations improve the sustainability of ketogenesis

BHB salts complex includes sodium, calcium, magnesium and potassium, a ketone body that supports ketosis by providing an energy source when carbohydrate intake is low. Ketosis is a metabolic state where the body burns fat for fuel, and maintaining elevated BHB levels in the blood is key. A sustained release preparation ensures a consistent BHB supply over several hours, avoiding rapid spikes and drops.

Also ketone supplement is a potential project as biofuel to power supply Implantable BCIs through enzyme. The similar theory about glucose fuel cell for Implantable electronics has been proposed.

Sustained-Release Preparations excel in delivering a prolonged, consistent effect with fewer doses and reduced side effects. They are well-suited for long-term ketosis management, such as in therapeutic settings or endurance activities, where maintaining steady ketone levels is key.

Formulation Design:

• Active ingredient: BHB salts complex (3:2:2:1);

• Sustained Release Polymer: Hydroxypropyl methylcellulose (HPMC) for control drug diffusion;

• Filler/Diluent: Microcrystalline cellulose for enhances tablet compressibility and bulk;

• Lubricant: Magnesium stearate;